Recently, the "Umbilical Mesenchymal Stem Cell Vesicles" (INCI number: 38292) (INCI name: Umbilical Mesenchymal Stem Cell Vesicles, trade name: CVEXSOTM), independently developed by Shenzhen Cell Valley Biomedical Co., Ltd.(hereinafter referred to as "Shenzhen Cell Valley"), has officially passed the review of the International Cosmetic Ingredient Naming Committee (INC) and been included in the "International Cosmetic Ingredient Dictionary and Manual". This certification marks a breakthrough in international standards for China enterprises in the field of bioactive cosmetic ingredients, injecting revolutionary technological power into the global anti-aging skincare market.
umbilical cord mesenchymal stem cell vesicles
An excellent vector for the "cell-free therapy" strategy
Umbilical cord mesenchymal stem cell vesicles (UCMSCVs) are the primary substances involved in paracrine signaling of stem cells and represent one of the most extensively studied and applied exosomes. They contain bioactive materials such as therapeutic growth factors and mRNA similar to those found in stem cells, exhibiting therapeutic effects including tissue repair and immune modulation. Additionally, they possess unique advantages such as: lack of self-replication capacity, absence of tumorigenicity; nanoscale size without capillary retention, enabling them to cross the blood-brain barrier and reach damaged sites in the central nervous system to exert biological effects. As a novel "cell-free therapy" strategy, they demonstrate therapeutic effects including immune modulation, anti-inflammatory action, anti-fibrosis, inhibition of oxidative stress, and enhancement of angiogenesis.
INCI attestation ：
China's ingredients are moving towards a "global passport"
The INCI name serves as the unique identifier for cosmetic ingredients in global R&D, production, and trade. Shenzhen Cell Valley completed the technical validation and application process over two years, and the successful certification of CVEXSOTM signifies:
Technical Authority: This ingredient can be labeled and used in global cosmetic formulations, becoming an internationally recognized active ingredient of the 'stem cell vesicle' type.
Industrial standardization: The WINCI database incorporates ingredient names, preparation processes, and quality specifications to establish traceable technical standards for the industry.
Market access advantages: Clearing regulatory barriers for downstream brands to enter international markets such as Europe, America, and Southeast Asia, and shortening the product launch cycle.
CVEXSOTM：
Rewriting the Anti-Aging Track with "Cell-Level Solutions"
CVEXSOTM, based on the proprietary “stem cell vesicle directed enrichment technology” of Shenzhen Cell Valley, overcomes the activity limitations of traditional exosome components:
Excelling in exosome quantity: Each vial contains up to 30 billion exosomes, ensuring users receive a richer supply of active ingredients.
Higher concentration of the original solution: The high-activity cell material used in the production of Cell Valley products can reach a concentration of 650 billion, which is at the world-leading level and demonstrates excellent performance.
Enhanced uniformity: The particle diameter of Cell Valley product is controlled within 55-60 nm, resulting in smaller and more homogeneous particles, which significantly improves absorption efficiency.
Stricter Testing: Cell Valley products meet higher standards after being inspected and approved by no fewer than two third-party testing institutions, with more rigorous quality control to ensure high quality and safety.
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Contact：Ms. Lai
Email：laijiaqi@rodael.com
Address：No. 1, Rongtian Road, Jinsha Community, Kengzi Street, Pingshan District, Shenzhen, China (Hepure Biomedical Ecological Park)
